Nepafenac is an ophthalmic NSAID used for the symptomatic treatment of pain and inflammation associated with cataract surgery. Nepafenac is a prodrug of Amfenac, an inhibitor of COX-1 and COX-2 activity.
Chemical name of Nepafenac is 2-amino-3-benzoyl benzene acetamide. Its molecular formula is C15H14N2O2 and molecular weight is 254.29.
Nepafenac is a yellow crystalline powder that is soluble in Dimethyl sulfoxide, slightly soluble in Acetone, Methanol and Chloroform, practically insoluble in Water. Its melting point is 178-180°C.
