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    Overview

    Lanatoside C is an antiarrhythmic agent, naturally occurring compound extracted from Digitalis lanata. It is a cardiac glycoside, a type of drug that can be used in the treatment of congestive heart failure and cardiac arrhythmia (irregular heartbeat).

    The substance is composed of four monosaccharides (glucose, 3-acetyldigitoxose and two digitoxoses) and an aglycon named digoxigenin. Chemical name of Lanatoside C is 3β,5β,12β)- 3-{[β-D- glucopyranosyl- (1→4)- 3-O-acetyl- 2,6-dideoxy- β-D-ribo- hexopyranosyl- (1→4)- 2,6-dideoxy- β-D- ribo- hexopyranosyl- (1→4)- 2,6-dideoxy- β-D- ribo- hexopyranosyl]oxy}- 12,14-dihydroxycard- 20(22)- enolide. Its molecular formula is C49H76O20 that corresponds to molecular weight of 985.12.

    Lanatoside C appears as a colourless or white crystals or white crystalline powder. It is odourless. Its melting point is 246-248°C.

    Clinical Applications

    Main indications of Lanatoside C are rapid response atrial fibrilation and paroxysmal supraventricular tachycardia, two common types of arrhythmia.

    Mode of Administration

    Lanatoside C can be used orally or by the intravenous route.

    Pharmacological Effects

    Lanatoside exerts positive inotropic effect by increasing the concentration of intracellular Calcium, thereby increasing myocardial contraction.

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